SRVF, A NOVEL HERBAL FORMULA INCLUDING SCROPHULARIAE RADIX AND VITICIS FRUCTUS, DISRUPTS FOCAL ADHESION AND CAUSES DETACHMENT-INDUCED APOPTOSIS IN MALIGNANT CANCER CELLS

Abstract When cells lose adhesion, they undergo detachment-induced apoptosis, known as anoikis.In contrast, tumor cells acquire resistance to anoikis, enabling them to survive, even after separating from neighboring cells or the ECM.Therefore, agents that restore anoikis sensitivity may serve as anti-cancer candidates.In this study, we constructed

Abstract Micro-computed tomography (micro-CT) is an X-ray-based technique that allows visualisation of the internal anatomy of insects in situ and does not require dissections.Traditionally, the study of insect anatomy has been mainly based on dissection techniques and microtome sections.However, micro-CT is becoming an increasingly widespread stud

The rivers, including Aras, in the Mughan region played an important role in the formation of the prehistoric sites.The Mughan Cooler Bag Plain has not received particular attention in terms of the archaeological investigations, as the extensive scientific activities concentrated on the Lake Urmia basin.Yataq-Tepesi is a prehistoric site in the cit

Over 20% of mortality during acute liver failure is associated with the development of hepatic encephalopathy (HE).Thus, HE is a complication of acute liver failure with a broad spectrum of neuropsychiatric Helmets abnormalities ranging from subclinical alterations to coma.HE is caused by the diversion of portal blood into systemic circulation thro